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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0346 [new locus tag: SACOL_RS01740 ]
  • pan locus tag?: SAUPAN001449000
  • symbol: SACOL0346
  • pan gene symbol?: —
  • synonym:
  • product: prophage L54a, N-6-adenine-methyltransferase

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0346 [new locus tag: SACOL_RS01740 ]
  • symbol: SACOL0346
  • product: prophage L54a, N-6-adenine-methyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 367591..368016
  • length: 426
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGAAGTACATTACAGTAGTAAAACAAACGAGTGGACAACACCACAACATTTATTTGAT
    GACCTAAGCGAAGAATTCAGTTTTACATTAGATCCTTGTTCAACAGACGAGAACGCCAAA
    TGCCGGAAGTATTATACAGTAAAAGATAATGGGTTAATTCAAGACTGGTCTGAGGACATT
    GTTTTTATGAACCCGCCATACGGTCGAAGTATTAAGCGTTGGGTCAAGAAGGCTTACGAA
    GAAAGTTTGAAAGGCGCAACGGTAGTTTGTTTAATACCCGCAAGAACAGACACGACATAT
    TGGCATGATTACATTTTTAATAAGGCTGATGATATAAGATTCCTACGCGGTCGTCTGAAG
    TTTGGAGATAGTAAAAACAGCGCTCCTTTTCCTAGCGCAATTATCGTTTATAGAGGTGCA
    CAATGA
    60
    120
    180
    240
    300
    360
    420
    426


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL0346 [new locus tag: SACOL_RS01740 ]
  • symbol: SACOL0346
  • description: prophage L54a, N-6-adenine-methyltransferase
  • length: 141
  • theoretical pI: 6.77433
  • theoretical MW: 16435.4
  • GRAVY: -0.634752

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.1.72?  ExPASy
    Site-specific DNA-methyltransferase (adenine-specific) S-adenosyl-L-methionine + adenine in DNA = S-adenosyl-L-homocysteine + N-6-methyladenine in DNA
  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage N-6-adenine-methyltransferase (TIGR01712; EC 2.1.1.72; HMM-score: 96.4)
    Genetic information processing DNA metabolism Restriction/modification phage N-6-adenine-methyltransferase (TIGR01712; EC 2.1.1.72; HMM-score: 96.4)
  • TheSEED:
  • PFAM:
    no clan defined Dam; DNA N-6-adenine-methyltransferase (Dam) (PF05869; HMM-score: 111.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9364
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.0628
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009647
    • TAT(Tat/SPI): 0.000654
    • LIPO(Sec/SPII): 0.002236
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEVHYSSKTNEWTTPQHLFDDLSEEFSFTLDPCSTDENAKCRKYYTVKDNGLIQDWSEDIVFMNPPYGRSIKRWVKKAYEESLKGATVVCLIPARTDTTYWHDYIFNKADDIRFLRGRLKFGDSKNSAPFPSAIIVYRGAQ

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]