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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL2661 [new locus tag: SACOL_RS13940 ]
- pan locus tag?: SAUPAN006370000
- symbol: SACOL2661
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL2661 [new locus tag: SACOL_RS13940 ]
- symbol: SACOL2661
- product: hypothetical protein
- replicon: chromosome
- strand: +
- coordinates: 2723588..2724046
- length: 459
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3237036 NCBI
- RefSeq: YP_187449 NCBI
- BioCyc: see SACOL_RS13940
- MicrobesOnline: 914128 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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421TTGAAAAAACTTCTTATTACCATCGTAATTATCGTATTAATCGGAGCACTTGGGTTCGCA
ATTTATGCTGCAATAAATCATTCTACATCATCAAGTAATAACCAAGAACAAGAAAATAAA
TCTACGCATAAAAAGACAGAAACCGAAGAAAATGATCAACAAGATGATAGTGCAGACAAA
ACAGATAAAAATCAAAATAATGGCAATAACGTTACTAATGACAATCAACCATCTTCACCG
TCAAATGTTCCTAACAACCATTCAACAGTACCATCGAATACGCAACCAGCTCAGCCAAAA
GACTCAAATTCAAATAAAAATAATACTCACGGTGGTGGCAGTCAATCGTCAACAAACAAC
CAAAATAATCAACAACAGAACACACCACCTGCTAATAAATCAAATAATACCAATACGCCT
TCTAAACAAACACCTCAAGCACAATCACCTAAAAATTAA60
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459
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL2661 [new locus tag: SACOL_RS13940 ]
- symbol: SACOL2661
- description: hypothetical protein
- length: 152
- theoretical pI: 7.85378
- theoretical MW: 16361.2
- GRAVY: -1.46579
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Cell division cell division protein ZipA (TIGR02205; HMM-score: 21.3)and 10 moreTransport and binding proteins Cations and iron carrying compounds cation transporter family protein (TIGR00860; HMM-score: 15.5)Cellular processes Sporulation and germination stage III sporulation protein AG (TIGR02830; HMM-score: 15.5)heavy metal sensor kinase (TIGR01386; EC 2.7.13.3; HMM-score: 13.4)Energy metabolism Electron transport sulfocyanin (TIGR03094; HMM-score: 13)Mobile and extrachromosomal element functions Plasmid functions entry exclusion protein TrbK (TIGR04361; HMM-score: 11.9)mycoides cluster lipoprotein, LppA/P72 family (TIGR03490; HMM-score: 11.7)Cellular processes Pathogenesis putative immunoglobulin-blocking virulence protein (TIGR04526; HMM-score: 8.8)two transmembrane protein (TIGR04527; HMM-score: 8.3)Transport and binding proteins Cations and iron carrying compounds potassium uptake protein, Trk family (TIGR00934; HMM-score: 5.8)Transport and binding proteins Nucleosides, purines and pyrimidines nucleoside Transporter (TIGR00939; HMM-score: 5.4)
- TheSEED :
- FIG01108077: hypothetical protein
- PFAM: no clan defined DUF4083; Domain of unknown function (DUF4083) (PF13314; HMM-score: 18.5)DUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 18)SpoIIIAH; SpoIIIAH-like protein (PF12685; HMM-score: 16.4)DUF5469; Family of unknown function (DUF5469) (PF17561; HMM-score: 16.4)SARAF; SOCE-associated regulatory factor of calcium homoeostasis (PF06682; HMM-score: 15.4)and 23 moreCytochromB561_N; Cytochrome B561, N terminal (PF09786; HMM-score: 14.6)Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 14.3)O-anti_assembly (CL0499) O-antigen_lig; O-antigen ligase like membrane protein (PF13425; HMM-score: 13.3)no clan defined TMEM51; Transmembrane protein 51 (PF15345; HMM-score: 13.3)DUF2206; Predicted membrane protein (DUF2206) (PF09971; HMM-score: 13.2)DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 12.9)UPF0767; UPF0767 family (PF15990; HMM-score: 12.7)DUF4199; Protein of unknown function (DUF4199) (PF13858; HMM-score: 12.4)Ac76; Orf76 (Ac76) (PF05814; HMM-score: 12.2)P12; Virus attachment protein p12 family (PF12669; HMM-score: 12)PsaL; Photosystem I reaction centre subunit XI (PF02605; HMM-score: 11.5)ABC-2 (CL0181) ABC2_membrane_2; ABC-2 family transporter protein (PF12679; HMM-score: 10.9)DMT (CL0184) TMEM144; Transmembrane family, TMEM144 of transporters (PF07857; HMM-score: 10.8)no clan defined SLC12; Solute carrier family 12 (PF03522; HMM-score: 10.7)Transporter (CL0375) Connexin; Connexin (PF00029; HMM-score: 9.8)GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 8.2)Cyclin (CL0065) CDK5_activator; Cyclin-dependent kinase 5 activator protein (PF03261; HMM-score: 7.9)OB (CL0021) tRNA_anti-like; tRNA_anti-like (PF12869; HMM-score: 7.9)no clan defined FAM176; FAM176 family (PF14851; HMM-score: 6.9)Tetraspannin (CL0347) Tetraspannin; Tetraspanin family (PF00335; HMM-score: 6.8)no clan defined MMM1; Maintenance of mitochondrial morphology protein 1 (PF10296; HMM-score: 5.8)FAM70; FAM70 protein (PF14967; HMM-score: 5.7)TipE; Na+ channel auxiliary subunit TipE (PF16972; HMM-score: 5.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.05
- Cellwall Score: 0.82
- Extracellular Score: 9.13
- Internal Helix: 1
- LocateP: Secretory(released) (with CS)
- Prediction by SwissProt Classification: Extracellular
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0.17
- Signal peptide possibility: 1
- N-terminally Anchored Score: -2
- Predicted Cleavage Site: YAAINHST
- SignalP: Signal peptide SP(Sec/SPI) length 23 aa
- SP(Sec/SPI): 0.895299
- TAT(Tat/SPI): 0.002039
- LIPO(Sec/SPII): 0.084029
- Cleavage Site: CS pos: 23-24. IYA-AI. Pr: 0.4477
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKKLLITIVIIVLIGALGFAIYAAINHSTSSSNNQEQENKSTHKKTETEENDQQDDSADKTDKNQNNGNNVTNDNQPSSPSNVPNNHSTVPSNTQPAQPKDSNSNKNNTHGGGSQSSTNNQNNQQQNTPPANKSNNTNTPSKQTPQAQSPKN
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
The Staphylococcus aureus proteome.
Int J Med Microbiol: 2014, 304(2);110-20
[PubMed:24439828] [WorldCat.org] [DOI] (I p)