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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS10575 [old locus tag: SACOL2025 ]
  • pan locus tag?: SAUPAN005279000
  • symbol: SACOL_RS10575
  • pan gene symbol?: agrC
  • synonym:
  • product: ATP-binding protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS10575 [old locus tag: SACOL2025 ]
  • symbol: SACOL_RS10575
  • product: ATP-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2083917..2085161
  • length: 1245
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2083917..2085161) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGATATTAATGTTTACAATACCAGCTATAATTAGTGGTATTAAGTACAGTAAACTTGAT
    TATTTTTTCATCATAGTAATTTCGACATTATCGTTATTTCTATTTAAAATGTTTGATAGC
    GCGTCCTTAATCATATTAACTTCATTTATTATTATAATGTATTTTGTCAAAATCAAATGG
    TATTCTATTTTGTTGATTATGACTTCGCAGATTATTCTATACTGTGCTAACTACATGTAT
    ATAGTTATATATGCATATATCACCAAAATTTCTGATAGTATATTTGTAATATTCCCTAGC
    TTTTTTGTAGTTTATGTGACTATTAGTATACTATTCTCATATATAATAAATAGAGTTCTC
    AAAAAAATTAGCACACCATATCTAATACTAAACAAAGGATTTTTAATAGTTATTTCGACT
    ATCTTACTGCTTACTTTTTCATTATTTTTCTTTTATTCACAAATAAACTCGGATGAAGCT
    AAAGTAATAAGGCAGTATTCTTTTATTTTTATTGGTATCACTATATTTTTAAGTATATTA
    ACATTTGTTATTTCTCAATTTCTCCTTAAAGAGATGAAATATAAACGTAATCAAGAAGAA
    ATTGAAACCTATTATGAATATACATTGAAGATTGAAGCTATCAACAACGAAATGCGCAAG
    TTCCGTCATGATTATGTCAATATCTTAACGCCACTTTCAGAATACATTCGAGAAGATGAC
    ATGCCTGGCCTACGTGATTATTTCAATAAAAATATTGTACCTATGAAAGACAATTTACAA
    ATGAATGCTATAAAATTAAATGGTATCGAGAATCTTAAAGTACGTGAAATTAAAGGCTTA
    ATTACTGCGAAAATTTTACGTGCACAAGAAATGAATATTCCGATTAGTATCGAAATACCC
    GATGAAGTAAGTAGCATTAACTTGAATATGATCGATTTAAGTCGCAGTATTGGTATTATT
    CTTGATAATGCAATTGAGGCATCAACTGAAATTGATGACCCTATCATTCGCGTTGCATTT
    ATTGAAAGTGAAAATTCAGTAACGTTTATTGTTATGAATAAATGCGCTGATGATATACCA
    CGCATTCATGAATTGTTCCAAGAAAGTTTTTCTACTAAAGGTGAAGGTCGTGGTTTAGGT
    CTATCAACTTTAAAAGAAATTGCTGATAATGCAGACAATGTCTTATTAGATACAATTATC
    GAAAATGGTTTCTTTATTCAAAAAGTTGAAATTATTAACAACTAG
    60
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    1020
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    1140
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    1245

Protein[edit source | edit]

Protein Data Bank: 4BXI

General[edit source | edit]

  • locus tag: SACOL_RS10575 [old locus tag: SACOL2025 ]
  • symbol: SACOL_RS10575
  • description: ATP-binding protein
  • length: 414
  • theoretical pI: 5.01931
  • theoretical MW: 47979.3
  • GRAVY: 0.476087

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    His_Kinase_A (CL0025) HATPase_c_5; GHKL domain (PF14501; HMM-score: 66.3)
    HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (PF02518; HMM-score: 17.9)
    GHD (CL0369) Glyco_hydro_30C; Glycosyl hydrolase family 30 beta sandwich domain (PF17189; HMM-score: 14.4)

Structure, modifications & interactions[edit source | edit]

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.11
    • Ymax_pos: 12
    • Cmax: 0.143
    • Cmax_pos: 42
    • Smax: 0.144
    • Smax_pos: 1
    • Smean: 0.115
    • D: 0.112
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_078061422 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MILMFTIPAIISGIKYSKLDYFFIIVISTLSLFLFKMFDSASLIILTSFIIIMYFVKIKWYSILLIMTSQIILYCANYMYIVIYAYITKISDSIFVIFPSFFVVYVTISILFSYIINRVLKKISTPYLILNKGFLIVISTILLLTFSLFFFYSQINSDEAKVIRQYSFIFIGITIFLSILTFVISQFLLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRHDYVNILTPLSEYIREDDMPGLRDYFNKNIVPMKDNLQMNAIKLNGIENLKVREIKGLITAKILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIGIILDNAIEASTEIDDPIIRVAFIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGLGLSTLKEIADNADNVLLDTIIENGFFIQKVEIINN

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS10575 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 1.34 1.35 1.36 1.37 1.38 1.39 1.40 1.41 1.42 1.43 1.44 1.45 1.46 1.47 1.48 1.49 1.50 1.51 1.52 1.53 1.54 1.55 1.56 1.57 1.58 1.59 1.60 1.61 1.62 1.63 1.64 Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
    Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
    J. Proteome Res.: 2011, 10(3);1139-50
    [PubMed:21166474] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]